The arguments used in the `/main/src/knock_out_simulation.py` file
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This file contains details about the Knockout Simulation arguments.
The default arguments for this script are as follows:
cmd = ' '.join(['python3' , 'knock_out_simulation.py',
'--context-model', '"{}"'.format(tissueSpecificModelfile),
'--context-name', '"{}"'.format(context),
'--disease-name', '"{}"'.format(dis),
'--disease-up', '"{}"'.format(Disease_Up),
'--disease-down', '"{}"'.format(Disease_Down),
'--raw-drug-file', '"{}"'.format(drug_raw_file),
'--reference-flux-file', '"{}"'.format(ref_flux_file),
#'--test-all'
])
!{cmd}
Argument | Required? | Default Value | Description |
---|---|---|---|
--context-model |
Yes | None |
The context-specific model file, (must be .mat, .xml, or .json |
--context-name |
Yes | None |
Name of context, tissue, cell-type, etc. |
--disease-name |
Yes | None |
The name of the disease |
--disease-up |
yes | None |
The name of the disease up-regulated file |
--disease-down |
Yes | None |
The name of the disease down-regulated file |
--raw-drug-file |
Yes | None |
The name of the raw drug file |
--reference-flux-file |
No | None |
The name of the reference flux file |
--test-all |
No | False |
Test all genes, even ones predicted to have little no effect |